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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cdc9fcc13de4ea944e1864e7688d6e5f5915051ddccf81984075782b4656c48' 
  AND token = 'rntaZ8qBtFTTyEAmCWvJ8CJJrg7xPqg49X+lxM3CdtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}