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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881d33561bf3e55ca9609d5997688a1c016ea0c99cbea765f8591c7d0a373dae' 
  AND token = 'JNpL8rCkYe7sdJGWStFrmMDOFN4Y+t8XUWuKeDPJuUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}