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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d149500f53299e6646ab1f131f4c81c3ff3ca6ca54e6f890a1a4586072a0ab6' 
  AND token = 'TPCcn+no3mHSf46QHHzIUDQV/39hH+Rt+KnXi8iz4X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}