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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdfa3fc411f5d5f72587fa61f4aa76865d62bbc6cddccb65e33f88cea563f430' 
  AND token = 'VGUTPTZD0PeAssm/yb+DmTd1D8lF8MJc3o2T4Y4Ic30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}