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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e740367c6dd08ddd6a579f666150fb2acf096abfa5779a0430243026d3c4341' 
  AND token = 'ZDMknd5k4mGuLzFgcEIk86sfFbff4iwIT12d5xsHOdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}