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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2c83ae0440c6180f5d274be3e75e560aa01a7002bdc1db586e186a488a5f7f' 
  AND token = 'PnqSeYGXUC8Xp2Ju3X9XEQwS+AoB21nOu7OFgMxZnRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}