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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39182dd2c8b80c3daa26c639a8828df209a1e3ac1cf3aed10d9b29e616060a61' 
  AND token = 'JpAzEz6ZTBFJu6hmTftPGvqXLzUJ1C5kvbKh7cfE05M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}