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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa7c34f63b5a29efa957a3a3d7480ec1c657319a161a8035823636b8788aa537' 
  AND token = 'XRVrq7ZWC+S5cdVPA1z48Ac8S1g8Hj9oKEHdqbzr2ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}