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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed6e39545a6e660cebe81b01986a12e79841a378278efd39b0cf76da344f302' 
  AND token = 'WcPOHlJIigzt9GX4jfiSyipCaQsnMCLmkplWaBVGlj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}