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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b27e4078039a16ed62e56868e1d7e319b29785b7362629bb875b55f1a2f364' 
  AND token = 'A7ZC3ab4bFEQchCzIiNe18T+fJKt3p+EdycAnvEaSUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}