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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8f3d9f68d788862e53554f3980175219e7f0de237695d6f1c1d0ddfe888815' 
  AND token = 'xI6H8Yg+2Clu1UilI1X9xkMCJXn1Yrxs2Z9x/2ZQZgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}