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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900d9576f61954e8617b70aeb8b5d4cf9f727c1e6c02a5d440d4b0b19451f558' 
  AND token = '2Qum8SH6s0Emhj29dbaRdoyIxmq8FbdZDCitaDWYDfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}