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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45eb532abadcbdd2c43f0e5c3e9c7c5fe70dd58bf5e22980c416e1a4e5d1984f' 
  AND token = 'oUWAGlv4mNX6SpJAwfO2lrJAqBxJBXJ++L5f0yMOrSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}