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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00675996c57136067dffd49091f00fa708d03b335fe7315473e8f1ae1a5c289b' 
  AND token = 'E+6/1pcxJrY2IWNwM2eH7sXd8sFH3VoOrUeDv6iWbIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}