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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde44f38a243c79d233f1696b74888b500aad30e8fdbebe456098a0f6d58e622' 
  AND token = 'NMOTlbBRVL6RE1Z0JGmuvaDuxu8QeVWs9H8A1iUM1jY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}