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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2148021c65e0c8430fcfe00173e2f4ef78188d385cd7fea66871f2a86739d8c' 
  AND token = 'qxuf64+9ImyRCV9WZKHuOnkGiDDraIvj872nu8bELPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}