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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef1491f2aad08d1bccc4b608f9c17180a5d27726c2c669fe263179f5b7e6f83' 
  AND token = '/Ck3kF1TzugdA8XmhcQzjpHhZMZCrra4WOFlWgBEcLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}