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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfc2a5227c1ec30565a1492eb35e1eacfaa173a247714a48ebff55a772af342d' 
  AND token = '1tQ4v9YyhIip9gxj1QPA/1Y4XyfWXzG6CqriQMlKZSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}