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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b5abad76fb51c2ff7adb98b24c47b065f0b46064395e8c20761ffc8627a6e4' 
  AND token = 'RTfEp7J0h68bSMJAciBaleVHdFrhZMdqRgqrwrgGLbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}