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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b92a585adcb29e4fccd995e1a1b954490bd0d895891076a978e2f2865c2a394' 
  AND token = 'ubk6JneVEUWgbbVbU19F3IK9wChnKmulh4hZv2Y8Eg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}