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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d45217190ab4b1c21b2773397ed67327dc2841cfdebb3e8f1a4a6b95ad5e8ac' 
  AND token = 'HkdAt+tcB0gYGKQiRScBS0u6NqGFXU3dil0o2HN101k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}