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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a3c45cf82de273305ac48837016339f97a80e1c9d07ea8fa1edc3b3a53ced8' 
  AND token = 'E5fZ3LQia7M44g7oDcu+ugYkPrjAbSdvwZ1TSt5q8bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}