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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331fcd782e95d342c68681a256d8271cc7400886e06cf0d2f0d35e69be8b31a2' 
  AND token = '44xMUeN4btpdos8Nrc0d96faHROBrGASDjayij8XMog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}