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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2353071fb32c8ba0fd37c8f5c05f93e6fe85471749ac43ffa291915eea09c8' 
  AND token = '4rWEwe3gtRRidv8DvrVZoqDJQqd6CCvxGsLsmFrrVOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}