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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d038f1c8ceac9281be5ffa36b741bc6b0b804accf9d64e4c191857196a86549' 
  AND token = 'pUyQbNT98UkpaBM7537PHGNyFN4sfuFyyYS0EHGsjMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}