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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3db66884b4bca647c7f33780c3c06f825c59bee07e061148e7752107642a496' 
  AND token = 'HS6nFRHM+QOl1f+/75eoCRNIqigu/EVia0Yhv0BW6oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}