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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16680c2b0dc22a9086e1b86e3979da2b611febb2282e2b9889a13998d89dfb3' 
  AND token = 'y7P7s47MoItuRvJf32Jzwgv4zQA4MUlKhxA86JQrVI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}