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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07a843e3b8ba77c26d7a5fbd7051ae310e10288f2d1ae7e8d45f5ebd02778305' 
  AND token = 'kMUbDL53UHXM2oAYgteqiDO4r1ZeP5t+rv5gM5NLL9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}