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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec36c45362d3f4df6eb86e164e1d046b4c2db5b016d72110f948f065983fec5' 
  AND token = 'Rci2G33ZD/TTGnPQpwt6A8b6sUDezL37BGi4FjthTCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}