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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1691e3fa846436cca98d54341693e3a368a5b610cf94abef3e1f8bad2cd834' 
  AND token = 'DXap5/wWZO7GdSvy96qommwWeXSghGFSvJtOX6ElBkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}