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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de4250f393be9a5a05df9060f7282c072ac645f26de518b50aab9e06becd006' 
  AND token = '+vWH2kFBIogiE4bJSCizk+B/g6GEOQFgIAcGa55cnVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}