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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3c9159c589fdc4207c287b9f53f9f32c3e6d0e993bf6dd203cdef84e69efb4' 
  AND token = 'LUGSYC8eebqtXVEP2jtaC+g/RuI5H3INdr7Ck9LgOzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}