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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc46b2bb6ba02c2c2e817f2e6b576a9ce677dd571313e08c6358594edcb59ef' 
  AND token = 'KBpv5z0NiT2eWzukgec8NxMeEx63t5aPSaxY48Ec2m4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}