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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a094df53322dfa8c7d61273e782e307e2d7e0a0f5ee66604e104ebcb737db644' 
  AND token = 'kGrsyncQ7YAAHjQPQql5b2Oux10Ot4gOead+cI8Ay9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}