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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336a33dfe3961f24f588ad29e75c34a3fcc6f38ce1f7bd8376a78af91e616287' 
  AND token = 'lPrNqYr7Hee5x9hW2kGCdVE8LZOJEOAuMFF/sXoeDWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}