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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '507134dd0b0853d2208a01c3f01b48d630856860b5e9c86e8097dc83c55e6534' 
  AND token = '2PirFOL+NXqO9QbKmj1m5yghyOMsQ6ULj7ml2GjdAIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}