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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14824236d6c899560923f8626cec1d2e7beb8af0656d3b9be813e100237d0f44' 
  AND token = 'Ih8dw6vAm2WfuEwLnxYoI4pbMOdbkZV1vBrSAQNmCBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}