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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b008c295c8dc1c33590e09abdbada5da32b7787652e3b77c59c436c52b173e9c' 
  AND token = '7e2sa1IhUzWBnD3pNdUoN/XZ4tNNYb9WQ24NSuHtNqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}