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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c03db7debe24cbbb4a0e800bf366642ee434528f448d64cada69b27c0f4172f' 
  AND token = 'kPiyF9ctUNlHrmiFKI7dkOb6jnFxHc4b49wzV1TVxJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}