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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4528e908fea31d3b286c1ed61e68edb5ca967e077b62178f833ad3d34d5565d' 
  AND token = 'RphDoOT09tdTg0EIBH6UeMVaSFN1yAUg8ChxKXsJnvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}