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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a549353b37dd97d2bd1d505973bd57065290f2035eaf1b700b6d9debe73c49' 
  AND token = 'P72ljx339D66G9pD+dAwy82G2GIV4bJdn1u6dxAEnKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}