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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3d898012fe35b746914aaed5354a961500f313f2a060a6428bd2a341c71d56' 
  AND token = 'q+z9bPL3d9JYYZxedOx7CJaaLsiime+5O/3XU8aAtQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}