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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8cefe48d25e1b46681b3babcfa9064cdb53d6132a0530c59c95ceff1ca490b' 
  AND token = 'uzYYSfJ1Jg1PmNwj0pGFltwSbzTuxkTiVPby3wwR8Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}