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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c42fc88a18980345883b0a0d8ab101f8e83d3d3b42dfec3f70b8a289b7089bc' 
  AND token = 'tiyGe6qzoAn7DoVuVm9kUYjA5Sn3PJQvsX2APmKin7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}