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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ccfbe41580bc8cb800a5e5814533210d4316738c3d445ec49a4e47da87ba46' 
  AND token = '3PbmFxIS0UUgW/LNkXl3gJnVqkL/yDT5XI9LpOaeUrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}