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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c034a7f708cf77cbd0099eb01ef1177b6dba66fd08563895fccc5b5c0515de50' 
  AND token = 'iNTaDKifaqNXcBZRk1BMBYU1fzBUYJkdIRnXUkAC1Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}