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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363fa8915b07d50fc9af6a0599cc4ddfeba776ede544a6c04d967270e5096340' 
  AND token = 'hwhv0BxpS+8rjF8NHWSJP865ZpSRXwUlQhcfXlDBz5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}