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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7f2775613f5f37aad39ab51aeb18030054608d4f890db8b36f3dc8da61a951' 
  AND token = '/6Lo+DoVxHpd6K0iHOHaHG5Oky9qhDSwRR94C6rrde4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}