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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a5985b76bc51e2ae1a43589d77b47203236f9f9b31542bfb4f58ba1b1df006' 
  AND token = 'AaTxuHAJlLryyqb0+BWSoVJEO4AvgdqdQbKbhlEEZi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}