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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7380c370760179c75d726b89a03dc91ff8c43549972657b029e00f877858e1fc' 
  AND token = 'pZrycvJ6SUVpLZQaTYbTkZczNJ+tVz5lfG0Lu5OX1to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}